Injectables

BOTOX®

 

The cosmetic form of botulinum toxin, often referred to by its product name BOTOX®, is a popular non-surgical injection that temporarily reduces or eliminates frown lines, forehead creases, crows feet near the eyes and thick bands in the neck. The toxin blocks the nerve impulses, temporarily paralyzing the muscles that cause wrinkles while giving the skin a smoother, more refreshed appearance. Studies have also suggested that BOTOX® is effective in relieving migraine headaches, excessive sweating and muscle spasms in the neck and eyes.

 

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DYSPORT®

 

Dysport® is an injection containing abobotulinumtoxinA (Botulinum toxin type A). AbobotulinumtoxinA is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity.

 

  • Dysport® is used to treat the abnormal head position and neck pain that happens with cervical dystonia (CD) in adults.
  • Dysport® is also used to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults younger than 65 years of age for a short period of time.
  • Dysport® may also be used for other purposes not listed in this medication guide.
  • Dysport® is injected into a muscle. A doctor, nurse, or other healthcare provider will give you this injection.
  • Dysport® injections should be spaced at least 3 months apart.
  • Dysport® injection should be given only by a trained medical professional, even when used for cosmetic purposes.

 

Your injection may be given into more than one area at a time, depending on the condition being treated.

 

The effects of a Dysport® injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin. Do not seek botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injection.

 

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XEOMIN®

 

XEOMIN® is a prescription medicine that is injected into muscles and used:

 

  • To treat the abnormal head position and neck pain that happens with cervical dystonia (CD) in adults.
  • To treat abnormal spasm of the eyelids (blepharospasm) in adults who have had prior treatment with onabotulinumtoxinA (BOTOX).
  • To improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults for a short period of time (temporary).

 

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JUVÉDERM®

 

JUVÉDERM® is a smooth consistency gel made of hyaluronic acid, a naturally occurring substance in your skin that helps to add volume and hydration. Your healthcare professional eases JUVÉDERM® injectable gel under the skin to instantly restore your skin's volume and smooth away facial wrinkles and folds, like your “smile lines” or “parentheses” (nasolabial folds the creases that run from the bottom of your nose to the corners of your mouth).

 

JUVÉDERM® provides a smooth, natural look and feel so everyone will notice (but no one will know)! In fact, studies show superior results of JUVÉDERM® compared to a collagen-based dermal filler. With JUVÉDERM® the injection process takes only about 15 minutes and results are immediate. Plus, there's minimal recovery or downtime. So you can step into Dr. Acra’s office for treatment and step right back into your life. JUVÉDERM® is indicated for injection into the mid to deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds).

 

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VOLUMA®

 

As you age, it's not just about lines and wrinkles. Your cheeks can lose volume and skin may begin to sag. VOLUMA® is the first and only FDA-approved injectable gel to instantly add volume to your cheek area to correct age-related volume loss in adults over the age of 21. It can provide you contour and a subtle lift for up to two years with optimal treatment.

 

  1. Instant, natural-looking results that last up to 2 years with optimal treatment
  2. Non-surgical. The injection process can be performed during a brief office visit
  3. From the #1 selling family of fillers
  4. Made with proprietary VYCROSS™ technology
  5. Contains lidocaine to help improve comfort during treatment

RADIESSE®

 

Healthy young skin contains collagen that gives it volume, flexibility and strength. As part of the aging process, your own natural collagen breaks down, diminishing facial volume. This loss of elasticity and volume results in the wrinkles, facial lines and skin laxity that rob your skin of its youthful appearance.

 

Welcome Back Your Own Natural Collagen

 

The ideal way to achieve wrinkle reduction is by replenishing lost volume. With RADIESSE® wrinkle filler, you welcome back your own natural collagen to smooth out the signs of aging. That's because RADIESSE® wrinkle filler's unique formulation stimulates collagenesis – the production of new collagen – which results in increased volume for natural looking wrinkle correction that may last a year or more in many patients. It's also why more and more cosmetic surgeons, estheticians, and other medical professionals are choosing RADIESSE® wrinkle filler for long-lasting facial rejuvenation.

 

The RADIESSE® wrinkle filler difference:

 

  • Stimulates the body's own natural collagen production
  • Instantly corrects wrinkles
  • Results that may last a year or more in many patients
  • Now FDA approved to enhance patient comfort with lidocaine mixing
  • In just one syringe, many patients can achieve long-lasting youthful results. And now you can ask your doctor about the RADIESSE® treatment option that significantly improves comfort. Because treatment with RADIESSE® wrinkle filler is simple, quick, comfortable and convenient, with immediately visible results that last, more and more people are discovering that it is the natural choice for maintaining a more youthful appearance.

 

TREATMENTS

 

In this day and age, most of us are familiar with the importance of collagen. It's what gives your young skin its full, supple appearance. And when it breaks down, you may begin to see skin laxity and facial wrinkles. When the collagen goes away, it takes facial volume and elasticity with it, leaving you with a face that may look older than how you feel inside. If you aren't ready to grow old gracefully, treatment with RADIESSE® wrinkle filler can bring back your own natural collagen and restore facial volume, with results that may last a year or more in many patients.

 

Please make your appointment for this treatment.

Untreated stubborn etched-in

lines and wrinkles

Smoother, natural-looking skin

after BELOTERO BALANCE5

BELOTERO BALANCE®

 

Is a hyaluronic acid (HA) injectable filler that completely integrates into the skin tissue.2,3 While some fillers are designed to rebuild facial volume and structure, BELOTERO BALANCE® specifically treats moderate-to-severe etched-in lines and wrinkles such as vertical lip lines above and around the lips.4

 

Only BELOTERO BALANCE® is created using the proprietary Cohesive Polydensified Matrix (CPM) process5:

 

  • Produces a smooth, flexible gel
  • Blends into the natural structure of your skin
  • Gently fills stubborn etched-in lines and wrinkles

 

BELOTERO BALANCE®2,4:

 

  • Integrates with your skin’s tissue
  • Helps smooth your moderate-to-severe etched-in facial lines and wrinkles
  • Maintains normal movement and facial expressions
  • Feels natural to the touch

 

Please make your appointment for this treatment.

KYBELLA™

 

KYBELLA™ is the first and only FDA-approved injectable drug that contours and improves the appearance of submental fullness. KYBELLA™ allows you to further expand your aesthetic injectable portfolio and offerings to your patients.

 

Treatment with KYBELLA™ is customized by the physician to the patient’s aesthetic goals for an improved chin profile. Once the aesthetic response is achieved with KYBELLA™, re-treatment is not expected.1

 

KYBELLA™ is supplied in a pack of 4 single patient use 2 mL vials.

 

SUBMENTAL FULLNESS

 

Patients asking about their submental fullness may, at times, refer to it as their “double chin.”

It is a common, yet undertreated facial aesthetic condition that can:

 

  • Detract from an otherwise balanced and harmonious facial appearance1
  • Lead to an older and heavier look2
  • Impact a broad range of adults, including both women and men
  • Be caused by aging, genetics and/or weight gain3

 

According to a survey by the American Society for Dermatologic Surgery (ASDS), 68% of consumers are bothered by submental fullness—nearly as many as those bothered by lines and wrinkles around the eyes (71%).4

 

Please make your appointment for this treatment.

 

 

 

JUVÉDERM VOLBELLA®

 

 

 

 

 

 

 

 

 

 

 

 

 

 

JUVÉDERM VOLBELLA® XC injectable gel is for injection into the lips for lip augmentation and for correction of perioral rhytids in adults over the age of 21.

 

DUBLIN, June 1, 2016 /PRNewswire/ -- Allergan plc, (NYSE: AGN), a leading global pharmaceutical company, today announced that the company has received approval from the U.S. Food and Drug Administration (FDA) to market JUVÉDERM VOLBELLA® XC, for use in the lips for lip augmentation and for correction of perioral rhytids, commonly referred to as perioral lines, in adults over the age of 21.1 In clinical trials, JUVÉDERM VOLBELLA® XC was found to effectively increase lip fullness and soften the appearance of lines around the mouth in a majority of subjects through one year.1,2*

 

"Many of my patients are very bothered by the lines that can appear around the lips, known as perioral rhytids. Additionally, when seeking lip augmentation, patients want a smooth, result that is not drastic" said Dr. David E. Bank, clinical trial investigator and founder of The Center for Dermatology, Cosmetic & Laser Surgery. "JUVÉDERM VOLBELLA® XC adds fullness to the lips and softens the appearance of the lines around the lips.2 With JUVÉDERM VOLBELLA® XC I am able to subtly enhance my patients' pout."

 

"The FDA approval of JUVÉDERM VOLBELLA® XC further demonstrates Allergan's commitment to developing advanced products and technologies that allow healthcare providers to better address evolving patient needs," said Bill Meury, Chief Commercial Officer, Allergan. "Additionally, this approval brings to market a product unlike anything that is currently available in the United States. JUVÉDERM VOLBELLA® XC is formulated with VYCROSS®,2 a proprietary filler technology from Allergan, which yields smooth products that have been engineered to address specific patient concerns such as lip fullness, age-related volume loss in the cheek area, or perioral rhytids.3"

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

VYCROSS® blends different molecular weights of hyaluronic acid which contributes to the gel's duration.1,3 In addition, JUVÉDERM VOLBELLA® XC has been customized with a lower HA concentration (15 mg/mL), while still providing the long-lasting results healthcare providers expect from the JUVÉDERM® collection of fillers.1,4,5,6,7,8 This makes JUVÉDERM VOLBELLA® XC a soft, smooth gel appropriate for adding subtle volume to the lips and softening the appearance of perioral lines.1 Allergan first debuted this innovative VYCROSS® technology in the U.S. in 2013 with the FDA approval of JUVÉDERM VOLUMA® XC for age-related mid-face volume loss.4 Now JUVÉDERM VOLBELLA® XC is the latest addition to the JUVÉDERM®  collection of fillers, the number one selling collection of dermal filler products in the world,9 to receive FDA approval.

 

The safety and effectiveness of JUVÉDERM VOLBELLA® XC has been demonstrated in several clinical trials including the U.S. pivotal study where 168 subjects were treated with JUVÉDERM VOLBELLA® XC.  A 5-point scale was used to evaluate the effectiveness of the product for lip fullness and a 4-point scale to evaluate the effectiveness of the product for smoothing lines around the mouth.2 Approximately two-thirds of subjects treated with VOLBELLA XC showed improvement in lip fullness and perioral lines through 1 year. The safety of JUVÉDERM VOLBELLA® XC was observed to be similar to that of the control. The most common side effects were temporary responses at the treatment site such as swelling, tenderness, bruising, firmness lumps/bumps, rednesss, pain, discoloration, and itching. Most of these side effects resolved within 30 days.2

 

JUVÉDERM VOLBELLA® XC was first approved in Europe in 2011. Currently, JUVÉDERM VOLBELLA® XC is distributed in more than 70 countries, including markets in Europe, Latin America, Middle East, Asia Pacific, and Canada.  The JUVÉDERM® family of products, including JUVÉDERM® Ultra XC and JUVÉDERM® Ultra Plus XC are marketed and sold in more than 80 countries outside the United States.10

 

 

 

 

 

 

 

 

 

 

 

 

 

 

What precautions should my doctor advise me about?

 

  • Tell your doctor if you are pregnant or breastfeeding.  The safety of JUVÉDERM VOLBELLA® XC for use during pregnancy or while breastfeeding has not been studied
  • The safety of JUVÉDERM VOLBELLA® XC in patients under 22 years has not been studied
  • The safety and effectiveness of JUVÉDERM VOLBELLA® XC in areas other than the lips and perioral area have not been established in controlled clinical studies
  • Tell your doctor if you have a history of excessive scarring (e.g., hypertrophic scarring and keloid formation) or pigmentation disorders, as use of JUVÉDERM VOLBELLA® XC may result in additional scars or changes in pigmentation
  • Tell your doctor if you are planning other laser treatments or a chemical peel, as there is a possible risk of inflammation at the treatment site if these procedures are performed after treatment
  • Tell your doctor if you are on immunosuppressive therapy used to decrease the body's immune response, as use of JUVÉDERM VOLBELLA® XC may result in an increased risk of infection
  • Tell your doctor if you are using medications that can prolong bleeding, such as aspirin, ibuprofen, or other blood thinners, as this may result in increased bruising or bleeding at the injection site
  • Minimize strenuous exercise, exposure to extensive sun or heat, and alcoholic beverages within the first 24 hours following treatment

 

Please make your appointment for this treatment.

 

 

Juvederm Vollure®

 

"The FDA approval of JUVÉDERM VOLLURE™ XC demonstrates Allergan's imperative to develop next-generation HA fillers designed to meet different patient needs," said David Nicholson, Chief Research and Development Officer at Allergan. "This commitment to ongoing scientific research and development is one of the factors that make JUVÉDERM®, the number one selling collection of dermal filler products."3

 

JUVÉDERM VOLLURE™ XC is formulated with Allergan's proprietary VYCROSS® technology, which blends different molecular weights of hyaluronic acid, contributing to the gel's duration.4† Our first product featuring VYCROSS® technology, JUVÉDERM VOLUMA® XC, was FDA-approved to increase volume lost due to aging in the cheek area,5 followed by JUVÉDERM VOLBELLA® XC, FDA-approved for lip augmentation and correction of perioral rhytids.6

 

Now with JUVÉDERM VOLLURE™ XC, the advanced VYCROSS® technology yields a custom engineered injectable gel product which was studied in the nasolabial folds, the number one dermal treatment area. It delivers a long-lasting result, up to 18 months*, that patients appreciate.2,4,7

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

JUVÉDERM VOLLURE XC™ is specifically tailored with a balance of gel firmness and low cohesivity, yielding a versatile formulation that adds subtle volume for the correction of moderate to severe facial wrinkles and folds.2,4 "What's exciting about JUVÉDERM VOLLURE™ XC is that it was shown to last up to 18 months from the initial or touch-up injection in a majority of subjects, which is the longest lasting result shown in a clinical study in the nasolabial folds,"2 said Dr. Joely Kaufman, a board-certified dermatologist and clinical trial investigator. "As the number of patients seeking dermal filler treatments continues to grow,7 I am pleased that the technology created by Allergan has also followed that same trend, with a full range of products that will allow for tailoring of treatment based on specific patient needs."

 

The most common side effects seen in the clinical study were temporary injection site responses at the treatment site such as swelling, tenderness, bruising, firmness lumps/bumps, redness, pain, discoloration, and itching. Most of these side effects resolved within 1 week.2

 

JUVÉDERM VOLLURE™ XC injectable gel is for injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds in adults over the age of 21.

 

 

Please make your appointment for this treatment.

 

Restylane Defyne

 

Restylane® Refyne was approved for the treatment of moderate to severe facial wrinkles and folds. This gel is made with a flexible hyaluronic acid filler that uses XpresHAn technology, which creates gels that offer a wide range of flexibility and support. Like memory foam, this gel moves and molds with your natural movement and then returns to its natural shape, making it ideal for areas of the face where there is a lot of movement.

 

Restylane Defyne and Restylane Refyne are the only fillers on the market that have been shown in clinical trials to help maintain natural movement and expressions.

 

Please make your appointment for this treatment.

Restylane Refyne

 

Restylane® Defyne was approved for the treatment of wrinkles and deep folds of moderate to severe. It is a dermal filler of hyaluronic acid of last generation designed to help keep your skin while looking natural and as you really are by not losing the naturalness of their expressions.

 

Restylane® Refyne is designed with XpresHAn Technology™ to help soften laugh lines (nasolabial folds and marionette lines). This can help you restore a more natural look to your face while maintaining your facial expressions. So, you always look like you. Talk to your specialist and see for yourself why it’s worth it.

 

As skin loses elasticity with age, the lines that run from the sides of your nose toward the corners of your mouth (nasolabial folds) and the lines that run from the corner of your mouth toward the chin (marionette lines) appear more noticeable. Restylane Refyne is a specifically formulated hyaluronic acid dermal filler made with XpresHAn Technology™ that helps correct these lines for a more natural look to your face. The unique cross-linking of the gel in Restylane Refyne is also designed to help support your natural expression—for real-life results that help maintain natural movement when you're smiling, frowning and even puckering up.

 

In a clinical study, subjects were evaluated based on perception of the naturalness of facial expressions in motion after 1 month of Restylane Refyne and Restylane Defyne optimal treatment.

 

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